---
product_id: 767854198
title: "Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)"
brand: "designs for health"
price: "663 Lei"
currency: RON
in_stock: true
reviews_count: 5
category: "Designs For Health"
url: https://www.desertcart.ro/products/767854198-homocysteine-supreme-methylated-b-vitamins-with-riboflavin-b6-b12-folate
store_origin: RO
region: Romania
---

# Bioactive 5-MTHF & P5P for superior absorption Vegetarian, Non-GMO, clean formula Methylated B vitamins for brain & heart Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)

**Brand:** designs for health
**Price:** 663 Lei
**Availability:** ✅ In Stock

## Summary

> 🧬 Elevate your wellness game with methylation mastery!

## Quick Answers

- **What is this?** Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules) by designs for health
- **How much does it cost?** 663 Lei with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.ro](https://www.desertcart.ro/products/767854198-homocysteine-supreme-methylated-b-vitamins-with-riboflavin-b6-b12-folate)

## Best For

- designs for health enthusiasts

## Why This Product

- Trusted designs for health brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Conscious:** Non-GMO, soy & gluten-free, perfect for mindful wellness seekers
- • **Brain & Heart Synergy:** Promotes cognitive clarity and cardiovascular resilience
- • **Advanced Bioavailability:** Methylated folate, B12 & P5P ensure maximum nutrient uptake
- • **Clinically Trusted Formula:** Preferred by functional medicine pros for proven results
- • **Optimized Methylation Power:** Supports efficient homocysteine metabolism for detox & vitality

## Overview

Designs for Health Homocysteine Supreme delivers a potent blend of methylated B vitamins, L-serine, and TMG to optimize homocysteine metabolism, supporting brain function, heart health, and detoxification. This vegetarian, non-GMO formula is clinically trusted by functional medicine practitioners and designed for superior absorption with bioactive folate, B12, and P5P.

## Description

Product description Homocysteine Supreme, a methylated multivitamin for men and women contains synergistic nutrients, including a folate supplement in the bioidentical, bioactive form, 5-methyltetrahydrofolate, known to facilitate the efficient metabolism of homocysteine. This methylated vitamin B supplement maintains a healthy homocysteine pathway, allowing for the normal production of its necessary and important end products. These include the sulfur-containing amino acids taurine and cysteine, and the neurotransmitters norepinephrine and dopamine. An optimally functioning homocysteine pathway provides methyl and sulfur groups for biochemical reactions, such as detoxification, healthy immune function, ideal joint and cartilage structure/joint support, and brain health and cardiovascular health, and thus is sometimes used as a supportive brain health supplement. Also includes vit B6 as B6 P5P, methylated folate and B12 supplements. Folate supplement for women and men.* Ingredients Main - Vitamin B2, Vitamin B6, Folate, Vitamin B12, Trimethylglycine. See supplement facts for full list of ingredients. P.when('A').execute(function(A) { A.on('a:expander:toggle_description:toggle:collapse', function(data) { window.scroll(0, data.expander.$expander[0].offsetTop-100); }); }); Directions As a dietary supplement, take two capsules per day with meals, or as directed by your healthcare practitioner. Safety Warning * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Take under the supervision of a medical professional. See more

Review: At last, a formulation with all bioavailable forms of B vitamins with added TMG. Even the B6 is in the form of P-5-P, which is important for nerve health. However, I bought this to help bring down my Homocysteine, which was elevated even when taking other B Complex formulas. This really did what it says on the label as it brought my Homocysteine level back down to a healthy as shown by my blood tests. I will keep buying this as it works.
Review: Recommended by my functional medicine doctor, and it’s been great so far! Excellent quality and value, and I don’t notice any taste when taking it—which is a big plus.

## Features

- Methylation Support - A modified methylated B complex with L-serine and TMG, which are known to facilitate the efficient metabolism of homocysteine and normal methylation.*
- Promotes Heart & Brain Health - An optimally functioning homocysteine pathway plays a role in biochemical reactions, such as detoxification, healthy immune support, ideal joint and cartilage structure, brain health and cardiovascular health.*
- Premium B Vitamins & TMG for Superior Absorption - Supplies a methylated folate and B12 supplement, along with P5P vitamin B6 and riboflavin. Includes Trimethylglycine to support normal methylation.*
- Vegetarian & Non-GMO - Vegetarian-friendly and made without soy, gluten, GMOs or soy. Take 2 capsules per day with meals or as directed by your health-care practitioner.
- Clinically-Trusted Care - DFH is the 1 practitioner supplement brand recommended by functional medicine professionals and the 1 practitioner supplement brand personally trusted by functional medicine professionals

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0050DZF2U |
| ASIN  | B0050DZF2U |
| Additives | B Vitamins, TMG, L-serine |
| Age Range Description | Adult |
| Best Sellers Rank | 39,745 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 361 in Vitamin D |
| Brand | designs for health |
| Country of origin | USA |
| Country of origin  | USA |
| Customer Reviews | 4.8 4.8 out of 5 stars (576) |
| Customer reviews | 4.8 4.8 out of 5 stars (576) |
| Date First Available | 22 Feb. 2022 |
| Format | Capsule |
| Is discontinued by manufacturer  | No |
| Manufacturer  | Designs for Health |
| Manufacturer reference  | HYS120-AZ |
| Product Dimensions  | 7.62 x 7.62 x 12.7 cm; 1 g |
| Serving Recommendation | 2 Capsules |
| Units | 120.0 count |

## Product Details

- **Brand:** designs for health
- **Diet type:** Vegetarian
- **Flavour:** Unflavoured
- **Item form:** Capsule
- **Primary supplement type:** Methylation Support Capsules

## Images

![Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules) - Image 1](https://m.media-amazon.com/images/I/71MJPWBVXBL.jpg)

## Questions & Answers

**Q: Curious why NAC was removed from the ingredients.**
A: Not just NAC, but zinc,B2, serine and chloline dihydrohen citrate

**Q: Does the Homocysteine Supreme contain turmeric?**
A: No, it contains riboflavin, vit. B-6, folate,vit. B-12, trimethylglycine, and L-serine. additional ingredients are cellulose/microcrystalline cellulose, ascorbyl palmitate, dicalcium phosphate, and silicon dioxide

**Q: Designs for health is the product manufacturer - who is the seller on Amazon?**
A: It's sold by the Designs for Health store on Amazon.

**Q: Does this product contain Bromelain in it?**
A: I just checked the label and I don't see Bromelain mentioned anywhere on the label. Hope this helps you.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by K***S on 30 January 2026*

At last, a formulation with all bioavailable forms of B vitamins with added TMG. Even the B6 is in the form of P-5-P, which is important for nerve health. However, I bought this to help bring down my Homocysteine, which was elevated even when taking other B Complex formulas. This really did what it says on the label as it brought my Homocysteine level back down to a healthy as shown by my blood tests. I will keep buying this as it works.

### ⭐⭐⭐⭐⭐ Review
*by T***. on 18 October 2025*

Recommended by my functional medicine doctor, and it’s been great so far! Excellent quality and value, and I don’t notice any taste when taking it—which is a big plus.

### ⭐⭐⭐⭐⭐ Review
*by J***Y on 27 August 2025*

Excellent product for high homocysteine levels, have had no negative side effects at all, and it does provide a small boost of energy, very smooth effect, and significantly lowered my homocysteine levels.

## Frequently Bought Together

- Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)
- Designs for Health Vitamin D Supreme - Vitamin D 5000 IU with 2000mcg Vitamin K as MK4 for Bone Health, Heart Health & Immune Support - Vitamin D3 Enhanced with GG Supplement (60 Capsules)
- Designs for Health Magnesium Glycinate Complex - Chelated Magnesium Bisglycinate + High Absorption Magnesium Oxide for Heart Health, Immune Support & Bone Strength - Vegan (120 Capsules)

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*Product available on Desertcart Romania*
*Store origin: RO*
*Last updated: 2026-02-28*