Targeted Genes: MTHFR, C677T, A1298CEveryone has an MTHFR gene, and many carry mutations of this gene that are caused by an inherited MTHFR variant associated with a decreased ability to metabolize folic acid and folate. In some cases, people with MTHFR mutations benefit from supplementing with methylfolate, which is the "bioactive" form of folate that helps to get around issues with folic acid in particular. Because these people have difficulty metabolizing folic acid, MTHFR support has been designed specifically to help those carriers of MTHFR "mutations" better metabolize folic acid to convert it into methyl folate which is itself an essential B vitamin. Carriers of the MTHFR polymorphisms C677T and A1298C in particular can benefit by the increased methylation function this supplement allows, along with the added benefits of the additional B12, B2, and B6 vitamins. B Vitamins Included in MTHFR Support: • B2: Riboflavin - Responsible for DNA repair, ATP (the energy currency of the body) generation. • B6: Pyridoxine - Assists in the synthesis of amino acids. • B12: Hydroxocobalamin - Plays a role in DNA synthesis and repair, as well as fatty acid and amino acid synthesis.
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