Vitamin D3- You may have heard some buzz about vitamin D and multiple sclerosis. There are some hopeful signs that it can ease your symptoms, but researchers still have a lot of work to do before we know for sure. "There's no perfect study," says Matthew McCoyd, MD, an MS specialist at Loyola University Medical Center. But some research suggests several ways that vitamin D can be good for you, whether you have MS now or want to keep it at bay: Slows down the disease. Researchers checked the symptoms of people in an early stage of MS. They found that after 5 years, those with more vitamin D in their blood had fewer problems. Prevents MS . Studies show that children who get a lot of sunlight, which is one way to get vitamin D, are less likely to get the disease when they grow up. Some research also shows that people who live away from the equator, where there's less sunlight, have a higher rate of MS. It's not yet clear how vitamin D helps, McCoyd says. It may be good for your immune system. This is your body's defense against germs, and when you have MS, it isn't working right. Antioxidants- MS is an immune-mediated disease, with inflammation and neurodegeneration contributing to neuronal demyelination and axonal injury. Current therapies for MS are directed toward modulation of the immune response; however, there is increasing evidence that oxidative stress is an important component in the pathogenesis of MS. The inflammatory environment in demyelinating lesions is conducive to the generation of reactive oxygen species. When these species are generated in MS and animal models of MS, products such as peroxynitrite and superoxide are formed that are highly toxic to cells. There are several examples of potential beneficial effects from various antioxidants in animal models of MS, but the efficacy may vary between different agents and, in some instances, may yield deleterious effects.
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