Dimethyl Sulfoxide, once considered a medical curiosity and is now used in many regulated drug delivery systems and healthcare applications. The Toxicological aspects of DMSO have been studied extensively (possibly more than any other substance) over a long period time. The conclusion is that DMSO has a very low toxicity rate and is a very low hazard in humans and animals via oral and parenteral routes. One of the highest concerns surrounding DMSO is that it can take everything through the skin. While DMSO by itself can penetrate easily through the skin and does enhance the adsorption rates of some chemical compounds. DMSO does not have the universal ability to take just anything through the human skin. Despite the research and past history, Dimethyl Sulfoxide is proven to be a safe versatile material. It should also be understood that when water is present as a cosolvent in DMSO the penetration kinetics are much lower.
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