Description This is an over the counter product - it does not require prescription.Comfort Zone with D.A.P. Wipes, 5 Count Clinical studies prove Comfort Zone® with D.A.P.® helps control: Excessive panting in 72% of dogs Vomiting in 81% of dogs Trembling in 85% of dogs Restlessness in 80% of dogs Controls destructive behavior in situations such as: Crate training Veterinarian visits Moving Unfamiliar environments How It Works: Mother dogs secrete dog appeasing pheromones to reassure their puppies that they are in safe surroundings. Comfort Zone® with D.A.P.® mimics these natural pheromones to help dogs feel comfortable and reassured in their environment. When dogs feel safe and secure, they are less likely to act out and be destructive. Comfort Zone® with D.A.P.® is not a drug or tranquilizer and does not affect humans or domestic pets other than dogs. Use only as directed. Directions for Use: Rub one wipe thoroughly in the crate, on furniture, car interior or other specific area. Apply to area until the wipe starts to dry, then dispose of wipe in wastebasket. The effect should last approximately 1 1/2 to 2 hours although each animal may respond differently. Also available in Diffuser or Spray formula. DO NOT USE DIRECTLY ON ANIMALS. KEEP OUT OF REACH OF CHILDREN. STORE AT ROOM TEMPERATURE. Precautions: Beware of potential spillage when opening the wipe. This product will not stain. If you have a concern, test the product on a sample which is not easily visible prior to use. In case of contact with eyes, wash them immediately with water and seek medical advice. Wear gloves if you have a known allergy to isopropanol. Ingredients: Canine appeasing pheromone...2%,  Isopropanol q.s...2.5 ml
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