The Promise Of Low Dose Naltrexone Therapy: Potential Benefits in Cancer, Autoimmune, Neurological and Infectious Disorders

I started taking Low Dose Naltrexone in early 2009 for my Hepatitis C and within months had tremendous results. My lab results showed a drop in my HCV viral load from over 1,500,000 to 47,000 and my liver enzymes had returned to normal for the first time since my diagnosis in 2002. It was at this time that I purchased "The Promise of Low Dose Naltrexone" and read it from cover to cover. It enabled me to have a better understanding on how LDN works, particularly on immune disorders, such as Hepatitis B and C: "In his studies on endogenous opiate, Ian Zagon has found that intermittent blockade of the receptor with low doses of opiate antagonist drugs upregulates production of endogenous opiates. Endogenous opiates such as metenkephalin and beta endorphin regulate homeostasis, immunity, wound healing and cellular removal. However, persistent blockade of the opiate receptor and persistent elevations of endogenous opiates, particularly metenkephalin, contribute to cell growth. Several studies of hepatic encephalopathy, Hepatitis B, and Hepatitis C show that higher levels of metenkephalin in the liver are associated with more severe liver damage, cirrhosis, and the development of hepatic encephalopathy. Persistent blockade stimulates cell growth, including cancerous cell growth, whereas intermittent blockade with LDN has an inhibitory effect and restores homeostasis. Along this line, low dose naltrexone has been shown to offer benefits in hepatic encephalopathy, viral hepatitis, and cholestasis-induced liver injury." Wonderfully researched and easy to understand, this book is a must for every researcher, physician or for anyone who is interested in learning more about LDN and how it can help most disorders.

It’s been a while since I read this book on Naltrexone therapy and its benefits. Even though there is an abundance of benefits in using Naltrexone, many doctors and PAs don’t readily accept it unless they’re already prescribing it to their patients.

This book is good overview of LDN (where it came from, how it works, who it may help, etc). LDN is awesome! I have fibromyalgia. My girlfriend has Hashimoto's. We have both made significant improvements (like 70% better!!) since going on LDN. It's unlikely to get lots of pharma marketing dollars since it's very, very cheap. Patent has run out. So it's up to us patients to get the word out. People that have any autoimmune condition may benefit. Fibromyalgia, Hashimoto's, Crohn's Disease, Multiple Sclerosis (MS), and more. Check this out if you're looking for something to add into your treatment program that has little to no side effects, and could make a huge difference for your quality of life!!!

Kinda going to review the book, but also the LDN. I got this book to further my cause to get doc to prescribe the LDN for me (I have MS) it has helped. Unintended 'side effect"? It also eliminated my allergies. So the reason we have allergies must be from an under production of endorphins and enkephalins, kinda makes sense since they are used by the immune system for communications, and allergies is the body mistaking a harmless substance for a dangerous one. But the book is well written, everything it suggested I have found to be accurate. I'd recommend it

The Promise Of Low Dose Naltrexone Therapy: Potential Benefits in Cancer, Autoimmune, Neurological and Infectious Disorders This book treats a very important subject: the use of an inexpensive generic drug in an off-label manner to treat a host of immune system dysfunctions from MS, Crohn's Disease, and thyroid diseases to various cancers. The drug should be included among a great many standard of care options physicians freely use in the attempt to ameliorate suffering. Unfortunately this book probably won't accomplish that. The information is excellent but the writing is not of a level that would attract professional consumers of information. It is of supreme importance that doctors themselves are made aware of the benefits of low dose naltrexone. They often argue that there are no clinical trials to support its use and therefore cannot prescribe it. But that is not true. Doctors commonly use many drugs sans clinical trials for off-label purposes without thinking twice. They don't prescribe low dose naltrexone because they know nothing about it and therefore they do not discuss it among themselves. There are only a very few vehicles at hand capable of bringing low dose naltrexone to the attention of busy professionals and unfortunately this book is not among them. That said, the book will be of immense use to patients desperate to find answers as to how to avoid the dangerous drugs they are often forced to accept in lieu of real help and/or to find relief for aliments untreatable by any drug currently listed in the accepted panoply of drugs. But the onus of doing all the work is still on the backs of suffering patients. Another down side is the price: extremely high in consideration of the unprofessional level of writing.

Let me keep it simple. This is an outstanding piece of work that everyone with any inflammatory/autoimmune/cancer problems should read, and every doctor should read. Not everyone will understand it, but most people will realize the potential this medication has in treating chronic and life-threatening illness. I speak from experience and it is changing my life for the better after 20 years of difficulty. The authors have gone to great lengths to present objective information, and to indicate the need for continuing education concerning "low dose naltrexone" treatment.

If you have an autoimmune disease: get this book, read it and pass it on to your doctor! LDN give many patients their lives back.

Very enlightening read, I enjoyed it and found it very infornative. Low Dose Naltrexone is helping me at a very low dose for Lymes disease and co-infections/viruses.