yes the 27 inch imac will take this type of ram.it can take a total of 32 gigs in 4 slots(8 gigs each slot)if you choose to max it out but 16 gigs is plenty.the 21.5 inch imac is non user replaceable.

is this compatible with the latest "iMac with Retina 5K display"

I bought 16GB of RAM for my 27-inch iMac with Retina 5K that I purchased in Dec of 2014. It's working great! As others have said, install in slot 2 and 4. Basically, I didn't take out the original RAM from Apple and just inserted the ones I purchased. That's it. It was good to go. I upgraded from 8GB to 24GB.

Is this compatible with the Macbook Pro 2.6GHz i7 (Mid 2012)?

I think you have the 15-in model. I have the 13-in. Both mid 2012 are using ivy bridge circuitry means that memory kit can run just fine with your macbook. I still am running this kit for 15 months now with no issues.

Will this work in my mid 2010 13" Macbook Pro?

Contrary to the "yes" answer, it does not work with the mid 2010 MBP. Look for 1066 MHz for compatibility. I know because I tried this item with my MBP, and had to send them back.

ASIN	B008LTBJFW
Additional Features	nv: Company Program^Crucial Apple \| Configuration^1024Meg x 64 \| DDR Timings^CL=11 \| DIMM Type^Unbuffered \| Density^16GB kit (8GBx2) \| Error Checking^NON-ECC \| Megabytes^16384 \| Memory Type^DDR3 PC3-12800 \| Package^204-pin SODIMM \| Platform Category^DDR3 \| Replenishment Flag^N \| Speed^DDR3-1600 \| Voltage^1.35v/1.5v (Dual Profile) \| VolumeDiscountBucket^HIGH
Best Sellers Rank	#862 in Computer Memory
Brand	Micron
Column Address Strobe Latency	11
Compatible Devices	Laptop
Computer Memory Size	16 GB
Customer Reviews	4.8 out of 5 stars 9,124 Reviews
Data Transfer Rate	1600 MHz
Form Factor	Apple
Global Trade Identification Number	00649528762122, 00649528762139
Item Weight	0.02 Pounds
Manufacturer	Micron Consumer Products Group
Memory Speed	1600 MHz
Model Name	CT2K8G3S160BM
Number of Pins	204
RAM Memory Technology	DDR3
RAM Size	16 GB
Special Feature	nv: Company Program^Crucial Apple \| Configuration^1024Meg x 64 \| DDR Timings^CL=11 \| DIMM Type^Unbuffered \| Density^16GB kit (8GBx2) \| Error Checking^NON-ECC \| Megabytes^16384 \| Memory Type^DDR3 PC3-12800 \| Package^204-pin SODIMM \| Platform Category^DDR3 \| Replenishment Flag^N \| Speed^DDR3-1600 \| Voltage^1.35v/1.5v (Dual Profile) \| VolumeDiscountBucket^HIGH Special Feature nv: Company Program^Crucial Apple \| Configuration^1024Meg x 64 \| DDR Timings^CL=11 \| DIMM Type^Unbuffered \| Density^16GB kit (8GBx2) \| Error Checking^NON-ECC \| Megabytes^16384 \| Memory Type^DDR3 PC3-12800 \| Package^204-pin SODIMM \| Platform Category^DDR3 \| Replenishment Flag^N \| Speed^DDR3-1600 \| Voltage^1.35v/1.5v (Dual Profile) \| VolumeDiscountBucket^HIGH See more
UPC	100177437200 012300514866 163120438143 793936394618 780746836018 649528762122 012303270998 803982798008 080850194920 649528762139 088021512276
Unit Count	1.0 Count
Voltage	1.4 Volts

Crucial CT2K8G3S160BM 16GB Kit (8GBx2) DDR3/DDR3L 1600 MT/s (PC3-12800) SODIMM 204-Pin Memory For Mac

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